F-18/PSMA PyLarify

RadNet is now offering the newest FDA-approved PET/CT tracer for prostate cancer.

F-18/PSMA PyLarify


What is F-18 PSMA/PyL?

F-18 PSMA/PyL is an injected molecular tracer that targets PSMA, used for a PET/CT scan.

F-18 PSMA/PyL binds to the active extracellular site of a PSMA molecule with high affinity and visualizes prostate cancer cells but not normal (healthy) cells.


PET/CT combines the images from a positron emission tomography (PET) (molecular scan) with those of a computed tomography (CT) (anatomic scan). The PET and CT scans are done at the same time with same machine. Together, they provide detailed images of anatomy and function of organs and tissues inside your body.

PET/CT is a way for physicians to learn accurate information about your cancer including  stage, spread and how you are responding to treatment.

What is PSMA?

PSMA is a protein expressed in all prostate tissue.

95% of prostate cancer cells overexpress PSMA, making it an outstanding imaging marker for primary prostate tumor and metastases.

Which Prostate Cancer Patients are Candidates for PET/CT with F-18 PSMA/PyL?

F-18 PSMA/PyL is approved by the FDA for:

  • Initial Staging – Prostate cancer patients with suspected metastases who are candidates for initial definitive treatment
  • Biochemical Recurrence (BCR) – Prostate cancer patients with suspected recurrence based on elevated PSA level

What is the Prep for this Scan?

  • No fasting required
  • Not glucose dependent
  • OK to take all medications

RadNet Locations for PET/CT F-18 PSMA/PyL

Arizona Diagnostic Radiology Apache Junction

1840 W Apache Trail, Apache Junction, AZ 85120

P: 480-288-6400 | F: 480-288-4079

Beverly Tower Wilshire Advanced Imaging Center

8750 Wilshire Blvd, #100, Beverly Hills, CA 90211

P: 310-689-3100 | F: 310-601-1446

Elite Advanced Imaging

17260 Bear Valley Rd, #109, Victorville, CA 92393

P: 760-951-2867 | F: 760-951-7473

Healthcare Advanced Imaging

4500 Olivewood Avenue, #100 & #200, Riverside, CA 92501

P: 951-682-7580 | F: 951-682-2143

Imaging Specialists of Pasadena

630 S Raymond Ave, #210, Pasadena, CA 91105

P: 626-356-0700 | F: 626-356-0400

Kern Radiology Bahamas

2301 Bahamas Dr, #01, Bakersfield, CA 93309

P: 661-324-7000 | F: 661-334-3164

Liberty Pacific Advanced Imaging Tarzana

18133 Ventura Blvd, #100, Tarzana, CA 91356

P: 818-933-2020 | F: 818-342-0303

NorCal Imaging Walnut Creek

114 La Casa Via, #100 & 200, Walnut Creek, CA 94598

P: 925-937-6100 | F: 925-938-9940

Rancho Mirage Interventional Radiology & Imaging Center

35800 Bob Hope Dr, #150A, Rancho Mirage, CA 92270

P: 760-770-1920 | F: 760-770-8345

Rolling Oaks Radiology Thousand Oaks

415 Rolling Oaks Dr, #230, Thousand Oaks, CA 91361

P: 805-778-1513 | F: 805-777-3846

Temecula Valley Advanced Imaging Murrieta

25455 Medical Center Dr, #100 Murrieta, CA 92562

P: 951-696-4230 | F: 951-696-4240

Temecula Valley Advanced Imaging

Temecula Parkway 31775 De Portola Rd, #100 Temecula, CA 92592

P: 951-587-8956 | F: 951-587-8290

Valley Metabolic Imaging

6121 N Thesta St, #207 Fresno, CA 93710

P: 559-449-2640 | F: 559-432-7020

WaveImaging Irvine Barranca

4050 Barranca Pkwy, #160 Irvine, CA 92604

P: 949-726-9500 | F: 949-753-9030

WaveImaging Newport Beach

3300 West Coast Highway, #B Newport Beach, CA 92663

P: 949-646-4400 | F: 949-753-9030

WaveImaging Orange

230 S Main St, #101, Orange, CA 92868

P: 714-978-2937 | F: 714-978-2518

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